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Ativan hallucination12/16/2023 Ces dispositions se reflètent par une réduction de l’utilisation de nombreux opioïdes puissants en faveur du tramadol. Les tendances de prescription récentes reflètent les efforts menés par les gouvernements américain et canadien pour réduire l’utilisation d’opioïdes. The relative risk of hallucinations from tramadol compared with other opioids remains unclear. The mechanism underlying TAH remains poorly understood and likely involves numerous receptor types. Tramadol-associated hallucinations can result in auditory or visual disturbances, although multisensory symptoms have also been reported. Of the 31 cases of “probable TAH”, 16 cases were “isolated TAH” while the remaining 15 cases belonged to “other existing medical condition”. Among these 101 cases, 31 were “probable TAH” and 70 were “possible TAH”. After a thorough screening, 34 articles comprising 101 patients reported an association between tramadol use and hallucinations. No observational studies or randomized clinical trials were identified with our systematic review only case reports were found. ResultsĪ total of 941 articles were identified in the initial search. We then conducted a narrative synthesis of the available literature to contextualize these results. The “probable TAH” cases were further classified as “isolated TAH” if hallucinations were the primary complaint, or “other existing medical condition” if concurrent signs and symptoms alluded to a diagnosis of an existing medical condition. Cases were categorized as “probable TAH” if the evidence supported an association between hallucinations and tramadol use, or “possible TAH” if hallucinations were attributed to tramadol use but the supporting evidence was weak. For all corresponding cases reporting hallucinations secondary to tramadol use, we extracted data on patient demographics, medical management, and the details on hallucinations. We conducted a systematic literature search in Embase, Medline, Cochrane CENTRAL, CINAHL, PubMed, Scopus, PAHO Virtual Health Library, MedNar, and to find reported cases of hallucinations associated with the use of tramadol. ![]() Despite the purported benefits of tramadol over other opioids, little remains known about tramadol-associated hallucinations (TAH). These provisions reflect a reduction in the use of many potent opioids in favour of tramadol. Recent prescribing trends reflect government-led efforts undertaken in both the U.S.
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